Certified Ophthalmic Medical Technologist (COMT) Practice Exam

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Study for the Certified Ophthalmic Medical Technologist (COMT) Exam. Prepare with insightful quizzes and multiple-choice questions that will enhance your understanding of ophthalmic technology. Get ready for your certification with confidence!

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What retinal finding can be caused by the drug Plaquenil, used to treat rheumatoid arthritis?

Macular degeneration
Bull's eye maculopathy
Retinal hemorrhage
Optic neuritis

The correct answer is: Bull's eye maculopathy

Bull's eye maculopathy is a characteristic retinal finding associated with the use of Plaquenil (hydroxychloroquine), which is commonly prescribed for conditions like rheumatoid arthritis and lupus. This condition is known to cause specific changes in the macula, resulting in a distinct pattern of parafoveal retinal pigmentary changes. These changes typically manifest as a 'bull's eye' appearance due to the loss of retinal pigment epithelium (RPE) and the accumulation of pigment at the fovea. This finding is a direct consequence of the drug's toxicity to the retinal cells, particularly after prolonged exposure or at higher doses. Early detection of bull's eye maculopathy is crucial since it can lead to permanent vision loss if not monitored and managed properly. Regular eye examinations, including visual field tests and optical coherence tomography (OCT), are important for patients on hydroxychloroquine to monitor for this potential adverse effect, highlighting the significance of understanding this specific retinal finding in clinical practice.